These modifications are detectable in a deep sequencing experiment, and if they are specific for miRNAs, incorporating them into a scoring system should further boost the identification of miRNAs.
Hence, using terminological resources such as Medical Subject Headings (MeSH) and Unified Medical Language System UMLSS) Metathesaurus help boost the identification performance (17, 18).
These boosted features facilitate figure-ground segmentation and the identification of targets in noise, diminishing the need for filtering by the parietal cortex.
Further improvements in sequencing technology together with the identification of novel RP genes will undoubtedly boost the success rate of NGS-based diagnostic approaches in RP in near future.
Alternatively, the identification of drugs that could boost exercise endurance (Woldt et al. 2013) or either complement or even reproduce the anticancer effects of CR without drastic changes in diet and lifestyle (i.e., CR mimics) is a goal for many pharmaceutical companies (Hursting et al. 2009).
Boosting the brightness of the signal received from calcific spots relative to normal parenchyma increases the detection and has been investigated in breast ultrasound (where the identification of microcalcification also carries significant clinical value) [17].
Implementation of similar ideas in a GWAS showed boosting in identification of disease-associated genes [ 14].
The identification of new compounds that can boost progerin degradation will significantly improve recovery for children affected by this syndrome.
Teamwork is an opportunity for mutual learning, it facilitates the identification of employees and the organization, boosts the quality of work and contributes to the achievement of the objectives of professionals and the organization [ 48– 50].
In particular, by utilizing the machine learning method of boosting trees we were able to create a predictive bioinformatics tool for the identification of proteins that are likely to play the role of a hub in protein interaction networks.
Taken together, proteomic analyses are boosting our knowledge of viral replication and disease etiology and are allowing the identification of new cellular targets that might be suitable for drug development.
