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Using the drive nuclease to repress key genes required for the non-homologous end-joining (NHEJ) pathway may increase the rate at which the drive is copied by boosting the effective rate of the competing homologous recombination (HR) pathway.
Parliament on Tuesday backed a set of one-off measures aimed at boosting the effective spending of €35 billion earmarked for Greece in the EU 2014-2020 budget.
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The method provides for a true random-effects analysis, or a "mixed-effects" analysis that allows one to boost the effective degrees of freedom by spatially regularizing the random-effects variance assuming that it resembles the spatial structure of the fixed-effects variance, which is well known.
Euro zone leaders last month agreed to boost the effective size of the fund to €440 billion, or $635 billion, and give it extra powers, including a potential role in helping to recapitalize banks.
We present a novel micro-heat pipe wick design and fabrication technique to significantly boost the effective thermal conductivity of the heat pipe relative to the monolithic substrate material.
In this paper, a pulse-width-modulation (PWM) technique is proposed for CT cascaded DSMs for on-chip automatic RC time constant tuning, which in turn enables the use of a correlated double sampling (CDS) technique to boost the effective dc gain of the opamp.
Such a change would boost the effective burden of state and local taxes--particularly in high tax states.
TPC estimates that the corporate tax boosts the effective tax rate of the highest-income 1 percent by 7.5 percentage points, more than five times the rate for the bottom 90percentt.
8 COBI acts as a pharmacoenhancer to boost the effective concentration of EVG.
Finally, it may be possible to repress genes required for the competing non-homologous end-joining pathway using Cas9 in order to boost the effective homologous recombination rate in a particular germline stage.
Today's business teams can often be spread out across the country or over a region, added Sharma, and employees need print capabilities from any device they use at all of their work locations, boosting the case for more effective cloud printing solutions in the marketplace.
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