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Effect size boosting occurs via reduction of non-BOLD noise at the subject-level and consequent reductions in between-subject variance at the group-level.
The major implications of whether boosting occurs or not, is to the two step strategy for IGRA testing of risk groups such as immigrants and household contacts.
Thus, it appears that the time point at which the second IGRA is done is highly relevant to the assessment of whether boosting occurs after TST.
The impact on modifying the threshold above which vector-based boosting occurs may be different for antibody responses compared to T cell responses, and this question will be addressed in future studies.
DOI: http://dx.doi.org/10.7554/eLife.07116.015 If VZV-CMI ≥ FoR, endogenous boosting occurs followed by an exponential decrease according to one of the scenarios described in the previous section.
A potential explanation is that memory responses to BCG are severely impaired in HIV-infected women, but boosting occurs though cross-priming of BCG memory cells by Mtb[ 42].
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Multiple studies show that lifting family income through safety net supports leads to measurable differences in academic achievement and attainment, especially if the boost occurs during early childhood.
Stereotype boost occurs when a positive aspect of an individual's social identity is made salient in an identity-relevant domain.
Although stereotype boost is similar to stereotype lift in enhancing performance, stereotype lift is the result of a negative outgroup stereotype, whereas stereotype boost occurs due to activation of a positive ingroup stereotype.
A similar immune system boost occurs in mosquitoes following bacterial challenge.
Specificity is enhanced in a majority of sequences and is dependent on mismatch type and adjacent base pairs; the largest discriminatory boost occurs for the central +C·C mismatch within the +T+C+C sequence and the +A·G mismatch within the +T+A+G sequence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com