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Boosting in infancy is attractive as there is a well established infrastructure within the EPI for such an additional vaccine.
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One option is to boost in infancy at about 4 6 months of age, and ideally this boost would coincide with an existing EPI schedule vaccine visit, providing no interference occurred between new and existing vaccines.
Quinvaxem, a fully-liquid, pentavalent combination vaccine containing inactivated hepatitis B (HepB), Haemophilus influenzae type b (Hib) and whole-cell pertussis (wP) antigens, and tetanus and diphtheria toxoids, has been shown to be suitable for boosting children primed in infancy with another DTwP HepB Hib vaccine.
In the absence of vaccine boosting, anti-PRP antibody levels induced by vaccination in infancy wane over 2 3 years (11 ).
However, even with full vaccination in infancy only 4 6 years of protection is provided, and boosting is required for long-term immunity (Fig. 2).
It starts in infancy.
Three siblings die in infancy.
Dickens left Portsmouth in infancy.
One girl died in infancy.
One brother died in infancy.
Tracking usually ends in infancy.
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