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The donor T cells exhibited the expected Th1 phenotype, i.e. IFNγ+TNFα+IL2+Foxp3− (Fig. 5A), and had regained IL-7Rα expression at the time of transfer (Fig. 5B). Figure 5C shows that rhIL-7 administration not only boosted the expansion of the infused Th1 cells but also maintained these cells at higher levels for a sustained period compared to the control group.

Wet climate may have boosted the expansion of the Mongolian Empire under Genghis Khan.

As a result, globalization greatly boosted the expansion of human wealth, benefiting both developed and developing countries alike.

Poly I C additionally led to increased expression of MHC class II and co-stimulatory molecules on CD8α+ DC (not shown) and strongly boosted the expansion of OT-II cells induced by the Ab antigen complex (Fig. 2B, D, E).

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Scientists are becoming increasingly convinced that a strange energy field described as the cosmological constant is boosting the expansion of the universe, causing it to accelerate.

High-speed rail is seen as a clean way to boost the expansion of China's transportation system, according to Dierkx.

To test this hypothesis, we used our established CD4+ ACT model to examine whether administration of exogenous IL-7 can improve the therapeutic outcome by boosting the expansion of polyfunctional CD4+ T cells.

The impending death of the Tevatron adds to a gloomy time for American science, coming as it does just as NASA has announced that its flagship project, the James Webb Space Telescope, is $1.6 billion over budget and will be years late, knocking the pins out from under hopes of mounting a mission anytime soon to investigate the dark energy that is boosting the expansion of the universe.

The brewer said the extra funds raised would further boost the expansion of its bar division, as well as fund a new series of "bottle shops" across the UK designed to cater for a growing demand for craft beer.

This demonstrated that PD-L silenced DCs exhibit enhanced stimulatory capacity to boost the expansion of adoptively transferred MiHA-specific CD8+ T cells in vivo.

Moreover, we demonstrate in immunodeficient mice that DC vaccination can boost the expansion of adoptively transferred MiHA-specific CD8+ T cells, in which PD-L silenced DCs show their superior stimulatory potential.

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