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"[The tracer] may help us design the next generation of cannabinoid-based medicines – for example, chemicals that boost the activity of brain marijuana-like compounds without directly activating cannabinoid receptors," says Daniele Piomelli, director of the Center for Drug Discovery at the University of California, Irvine.
We conclude that the START domain is not a transcriptional activator in the classical sense, since it was found to boost the activity of the transcription factor only when VP16-AD was also present.
It is known that vitamin D can boost the activity of certain genes and dampen down others.
That can boost the activity of the adjacent rice gene, which may produce noticeable changes in the plant.
Using optogenetics, the investigators were able to boost the activity of the diminished circuit in the mutant mice.
We report an approach to boost the activity of transferred antitumor CD8+ T cells by inhibiting ER stress or silencing Chop during the expansion phase.
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The merging process could also be the origin to boost the activities of its member galaxies.
One strategy to boost the activities of both enzymes was to optimize cofactor availability by supplementation with NAD+.
The eIF2B protein normally works to activate eIF2; Sidrauski, Tsai et al. observed that ISRIB boosts the activity of eIF2B and renders it insensitive to blockage by phosphorylated eIF2.
One theory is that CBD boosts the activity of other cannabinoids produced naturally by the brain.
Blocking this receptor actually boosts the activity of another receptor, known as the AMPA receptor.
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Justyna Jupowicz-Kozak
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