However, SRS is limited to small targets, and therefore this technique is preferred especially in small recurrent lesions or as a boost modality for macroscopic residuals in combination with external beam RT to the tumor bed [ 51].
To define the suitable Env derived immunogen, we systemically compared the immunogenicity of gp140 and gp145 in a DNA vaccination alone and a prime-boost modalities.
Several studies used successfully rBCG in heterologous prime-boost regimens with other vaccine modalities, whereby poxviruses, adenoviruses and virus-like particles as vectors delivered a strong boost for BCG-primed responses against the shared transgene products [3], [20], [46], [47].
The present study uses the Pk4 antigens to compare priming with three different vaccine modalities before poxvirus (Pox) boost: DNA plasmids, recombinant adenovirus 5 (Ad5) [21], [21], and recombinant alphavirus-derived viral replicon particles (VRPs) [20], [21].
Therefore, many researches are trying to design and develop a probe which can be detected by different imaging modalities so as to boost the clinical benefits of multimodality imaging.
Over the past decade, however, the use of clinician-performed, hand-carried, bedside ultrasound has gained increasing popularity as a useful imaging modality worldwide, helping to boost the diagnostic capacity of rural district hospitals in resource-limited settings.
To mimic performance enhancement in sports, and possibly to boost the effect of the intervention, both exercise modalities will be used in this trial.
Human studies have also shown superior immune responses during mixed modality prime-boost [ 27, 28].
Many hypothesize that an imaging modality such as ultrasound could help boost the diagnostic capacity of rural health care centers and thereby ameliorate care delivery by improving diagnostic accuracy to better use scarce resources [2 4].
Numerous cases suggest the benefits of the bLearning modality and the possibilities it offers to boost the development of skills in different disciplines.
