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It is possible that six weeks after treatment could have been too short a follow-up time to observe a significant boost in levels of IgE against SWA.
Among the women who received praziquantel at enrolment, there was a significant boost in levels of IgG1 (p < 0.001), IgG2 (p < 0.001), IgG3 (p = 0.011) and IgG4 (p < 0.001) against SWA at six weeks post-treatment (figure 2B).
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To address this gap in our knowledge, we also evaluated intracellular PGRN levels and detected no significant changes (Fig. 1A), which indicates the boost in exPGRN levels is likely due to inhibition of endocytosis.
The other interpretation, which EMBL's council and management are fervently hoping will win out, would require an average boost in 1995 levels of only 2.1%.
"It's a lie," biologist Elena Alvarez-Bullya told me bluntly, when I asked her whether the government's plan to begin experimenting with GM corn might give farmers a badly needed boost in production levels.
Obese subjects whose livers started out fatty, by contrast, responded to their moderate weight gain with higher blood pressure, an increase in insulin insensitivity, rising triglycerides, and a boost in their levels of "very-low density lipoproteins," which are strongly linked to cardiovascular disease risk.
The boost in prostaglandin levels within the peritoneal cavity then raises inflammatory pain by rising capillary permeability [ 34].
3. To examine the influence of pregnancy on the praziquantel-induced boost in antibody levels at six weeks post-treatment.
The boost in maturase levels along with a concomitant drop in activity rules out that SMDC increased maturase stability.
This boost in phosphorylation levels coincided with the presence of two PTS sugars, glucose and fructose, in the revival medium.
The change (boost) in antibody levels during pregnancy among women first treated during pregnancy was compared with the change after delivery among women first treated after delivery using linear regression based on log10 antibody concentration+1).
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