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In the PET-MR, the MRAC is still a matter of concern; the attenuation map does not differentiate between the soft tissue and bone, which can result in underestimation of the PET signal [19, 20].
Local stress peaks in the region of the interlocked screws can lead to a material failure of the bone, which can result in complications such as nail or screw brake-down and bone refracture.
However, a principal obstacle that is often encountered with surgical intervention in osteoporotic patients is the possibility of hardware pullout in spinal fusion due to the fragile characteristic of the bone, which can result from either micromotions/injuries or excess force applied at the bone-metal boundary [ 5].
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The disease causes chronic joint inflammation and progressive destruction of the cartilage at the ends of bones, which can result in an inability to use the affected joints.
Metastatic bone lesions eventually lead to bone weakening which can result in skeletal fractures, spinal cord compression, intractable bone pain, cachexia and death [ 4].
In the conventional ridge splitting technique, a complete flap is raised to allow adequate visibility of the bone defect which can result in disturbance of vascular supply and increase bone resorption rates.
Equally important is the fact that heparin has a propensity to induce immune-mediated platelet activation, which can lead to heparin-induced thrombocytopenia (HIT), and it has an effect on bone metabolism, which can result in osteoporosis.
An increased calcium excretion can be both the cause of, and an effect of, increased bone resorption, which can result in low BMD (osteopenia or osteoporosis) and increased risk of fractures [ 10, 11, 13].
In theory, a certain degree of interspinous elastic device loosening may occur after bone resorption, which can result in a mild decrease of the lumbar stability and subsequent postoperative pain and discomfort due to the stimulation of inflammatory factors produced during friction and bone resorption [ 37].
The relative slipping movements may change the dielectric constants and resistances of bone, which can lead to multiple relaxation time behaviors during the deformation process of bone.
For bone, this includes fragility, low bone mass, and progressive skeletal deformities, which can result in various degrees of short stature.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com