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Biochemical markers of bone turnover were not measured.
The other associations between calcium or phosphate excretion and bone turnover were not close to the statistical significance in the robust regression.
Although we saw differences in bone morphology between treatment groups, systemic measures of bone turnover were not significantly different among treatment groups following fracture.
Elderly osteoporotic women in sunshine abundant São Paulo, Brazil (23°S) who received 10 μg (400 IU) vitamin D3 daily for three months increased their mean s-25(OH D from 46.7 to 59.5 nmol/l, whereas PTH levels or bone turnover were not significantly affected [ 13].
Similar(56)
Obviously, the two explanations for AR-mediated protection against Lef1 haploinsufficiency – molecular interaction with the Wnt pathway and attenuation of bone turnover – are not mutually exclusive.
Of note is the observation that the resulting bony metastases do not show preference for particular skeletal sites where high bone turnover occurs, indicating that high bone turnover is not required for the establishment of metastases.
ERα has an important role in preventing osteoporosis, because males with a defective ERα develop severe osteoporosis and the increased bone turnover is not reversed by high-dose estrogen treatment [42].
The mechanism of IL-6 signalling in bone turnover is not yet understood.
This confirms the fact that bone turnover is not excessively reduced with zoledronic acid treatment.
The diminishing effect on BMD due to impaired bone turnover was not shown until six months of polychemotherapy [ 28].
The full picture of bone turnover is not completed as yet, although many factors and interactions are well described.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com