Sentence examples for bone turnover and increases from inspiring English sources

Ultimately, denosumab suppresses bone turnover and increases bone mineral density in both trabecular and cortical bone.

Small pilot studies suggest that patients who are treated for 3 years with a bisphosphonate, alendronate, and are then treated with PTH have a delayed response in biochemical markers of bone turnover and increases in bone mass over the first year compared with patients treated with raloxifene for 3 years prior to PTH [ 31].

Bisphosphonates exert their therapeutic effect by reducing bone turnover and increasing overall mineralization.

Inadequate intakes of vitamin D and calcium lead to reduced calcium absorption, higher bone turnover and increased bone loss and risk of fractures [ 22- 25].

Both drugs reduce bone turnover and increase bone mineral density, though alendronate has a stronger effect on these domains than raloxifene [ 8].

22 This event prompts an endless loop of increased bone turnover and increased tumor metastatic ability that may account for the central role of bone metastases in advanced prostate cancer.

In an extension of a previous trial, Bolland and colleagues 78 showed persistence of drug effect in men at two years after a second annual dose of zoledronic acid in suppressing markers of bone turnover and increasing bone mineral density.

4, 7 Vitamin D insufficiency causes greater secretion of parathyroid hormone (PTH) due to the low serum levels of calcium and active vitamin D, resulting in high bone turnover and increased bone resorption.

Both reduction in bone turnover and increase in hip BMD may be necessary to decrease the fracture risk of the hip, which is primarily composed of cortical bone and may require greater proportionate changes than trabecular bone (Epstein 2007).

It has been confirmed that the osteoporosis is a common skeletal disorder characterized by low bone density caused by decreased bone turnover and increased activity of osteoclasts [ 1– 9, 13, 49].

While lower doses of estrogen have been shown to reduce bone turnover and increase BMD, prospective evidence showing a reduction in risk for fracture with-low dose estrogen replacement is lacking.