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In the next series of experiments we sought to further strengthen the association between subchondral bone turnover and changes in weightbearing in this model of OA.
Because the effects of antiresorptive treatment on bone turnover and changes in BMD may vary with severity of bone loss [ 41], our study specifically informs the value of TC to post-menopausal women with a firm diagnosis of osteopenia.
When investigating the association between the rate of bone turnover and changes in periprosthetic BMD, biochemical serum markers were analyzed by quartiles with the two middle quartiles combined (lowest 25%, middle 50%, and highest 25%).
Because the aim was to assess the association between changes in markers of bone turnover and changes in BMD, the present study included only men who have been longitudinally followed for at least 3 visits with serum samples available during follow-up period.
A goal of the present pilot study is to collect preliminary biomechanical data, before and after a course of Tai Chi training, to evaluate Tai Chi's impact on lumbar and hip mechanical load, and to relate these data to clinical measures of bone turnover and changes in BMD.
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Comparisons have often been with tamoxifen, which itself may decrease bone turnover and change bone mineral density.
Secondary endpoints were the change in urine calcium, change in markers of bone turnover and change in BMD during 12 months.
Third, is there a causal relationship between changes in bone turnover markers and changes in femoral neck BMD?
Several studies have successfully reported the use of Tc-99 m-labelled diphosphonate compounds, e.g. methylene diphosphonate (MDP), hydroxymethane diphosphonate and hydroxyethylidene diphosphonate, to detect changes in bone turnover and cartilage composition in osteoarthritis models in rodents [47].
And variability that can not be controlled for, such as age, gender, menopausal status, diseases characterised by changes in bone turnover, and medications [ 8].
Risedronate daily, weekly, and monthly have similar BMD changes in the spine and hip, similar changes in markers of bone turnover, and morphometric vertebral fractures.
More suggestions(12)
bone fixation and changes
bone resorption and changes
bone size and changes
bone destruction and changes
bone turnover and increases
bone area and changes
bone strength and changes
bone development and changes
bone marrow and changes
bone volume and changes
bone degradation and changes
bone turnover and decreases
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