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Significant differences in qualitative histological characteristics of the compact bone tissue were not found although fewer secondary osteons were found in animals from the experimental groups.
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However, the bonding between titanium and bone tissue is not always strong enough and can become a critical problem.
The skeletal organ may undergo mineral loss with increasing age for various reasons, but the Ca concentration in mg g−1 in the remaining compact bone tissue is not expected to change.
Haversian bone tissue was not found.
Bone tissue is not only a highly vascularized tissue but also a highly neurotized tissue.
The mechanisms by which estrogen act on bone tissue are not completely understood.
The role of Fe in the bone tissue is not well understood.
The bone tissue was not in direct contact with implant surface.
The defect site was covered with little semitransparent tissues like the normal cartilage tissue and disconnected with the normal cartilage tissue; the subchondral bone tissue was not obviously exposed).
The defect site was covered with more semitransparent tissues like the normal cartilage tissue and connected with the normal cartilage tissue; the subchondral bone tissue was not obviously exposed).
Although at the histological level, bone tissue was not evident in the Wnt7b-rescue embryo, molecular analyses revealed upregulation of Runx2, AP and Osx within a small domain of the perichondrium at the diaphysis, as well as in the presumptive marrow cavity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com