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Furthermore, as HA is nonbiodegradable it cannot be replaced with new bone tissue over time [ 7].
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The results have shown that the regenerated bone tissue remodels over time, as indicated by a significant decrease in bone volume, total volume, and connectivity density combined with an increase in mineral density.
The tissue over time becomes chronically degenerative and sore.
Specifically, orthopedic biomaterials, whether bone scaffolds, plates or screws, must be able to withstand normal bone tissue loading at the time of implantation.
A significant dependence was observed between tissues over time.
For tissue engineering applications, bone tissue growth occurs over a period of 3 5 weeks.
H&E staining showed that no inflammatory response was observed and the new bone tissue was gradually increased in all groups over time with the degradation of the scaffolds.
This consideration is important because the dynamics of bacterial populations in soft tissues and bone differ greatly over time [ 3].
Some tissues heal normally others with scar tissue that over time often can remodel into normal tissue.
In particular, both trabecular bone thickness and trabecular bone separation distributions over time (4 8 weeks) differed significantly (P < 0.05).
Stabilization of the marginal bone level over time requires documentation.
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