Despite smaller bone size, thicker cortices and more plate-like trabecular bone in premenopausal Chinese American women led to 14% and 8% greater whole-bone stiffness at the radius and tibia, respectively, versus whites.
In this study, the Sham, LP20 and LP100 groups showed significantly higher bone stiffness at 9 weeks post-treatment compared to the OVX group.
With regard to the individual contribution of various aspects of cortical microarchitecture to whole bone stiffness, cortical TMD was the most significant single predictor of bone stiffness at both radial and tibial sites.
It is possible that early trabecular bone loss in the spine increases the risk of fracture, and that heterogeneous bone stiffness increases the risk [ 17].
As another parameter for bone stiffness we measured the bone volume which did not increase significantly.
We found a significant decline in BMD in the cortical but not the trabecular region, and a reduction in bone strength and stiffness at the contra-lateral side two years after a distal radius fracture.
We observed no correlation between the bone mineralization and stiffness at the microscopic scale either in the oim or in the wild type mice.
Typical load/deflection curves with both the elastic (linear) and plastic components separated by the yielding point as described by Burstein et al. [ 17] were obtained, enabling graphic determination of the following mechanical properties: maximal load, bone stiffness, and energy at failure.
