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Archival human temporal bone specimens from subjects ranging in age from 16 to 80 years old were used.
To investigate the role of subchondral bone changes in OA, articular cartilage and subchondral bone specimens from OA patients undergoing total knee replacement surgery or from non-OA trauma patients were analyzed.
Trabecular bone specimens from L2 vertebrae were collected from 51 recently deceased donors (54 95 years of age; 20 men and 30 women).
Using a combination of compression testing and micro-finite element analysis on a subset of cancellous bone specimens from that study, we calculated the hard tissue mechanical properties and the apparent (macroscopic) mechanical properties.
For example, bone specimens from sites at high latitudes usually yield better quality DNA than samples from temperate regions, which in turn yield better results than samples from tropical regions.
The aim of the present work is to revisit experimental data (elastic coefficients, porosity) previously obtained from 21 cortical bone specimens from the femoral mid-diaphysis of 10 donors and test the validity of the model by proposing a detailed discussion of its hypotheses.
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No discernable differences in biofilm growth were noted between whole-bone specimens of either A. mississippiensis or G. gallus, nor were any discernable differences identified between halved-bone specimens from the two respective taxa.
The NMR bound and mobile water changes were determined from cortical bone specimens obtained from normal and disuse turkey bones.
The bone specimens obtained from the patients were transferred to the laboratory and dried in an oven at 110°C until a constant weight was reached.
The second approach for analysis of peri-articular bone involves the analysis of subchondral bone specimens retrieved from human subjects or animal models at various stages of OA progression [ 3, 4].
Interestingly, when we examined H&E-stained tissue sections, we found presence of micro-metastatic colonies in PC3-Neo group, whereas no metastatic colonies were observed in bone specimens collected from PC3-PPP2CA group.
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