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Figure 1c shows the ER−/HER2− subgroup (70 patients), where bone metastases occurs in a little over 25% of the patients, and Figure 1d shows the HER2+ subgroup (62 patients) with ~33% of patients relapsing first at the bone site.
Figure 1a shows that after developing a metastatic tumor at the bone site, the two most probable second metastatic sites are lung/pleura, and liver, both representing roughly equal sector widths (around 10%).
In contrast, prematurity was not associated with volumetric trabecular and cortical densities at any measured bone site while the typical sex differences in bone density were observed.
In this paper, a neural network model is developed to simulate the accumulation of apparent fatigue damage of 3D trabecular bone architecture at a given bone site during cyclic loading.
No information is reported to date on the effectiveness of applying a mechanical loading in vivo on cell-seeded scaffold with respect to bone formation in a bone site.
The proposed approach is able to predict in rapid way some relevant outputs related to bone adaptation process such as trabecular bone density, elastic modulus and accumulation of apparent fatigue damage of 3D trabecular bone architecture at a given bone site.
The correlation coefficient (r) of the relationship between MIs (y) and cortical vBMD (x) at each bone site ("distribution/quality" curve that describes the efficiency of distribution of the cortical tissue as a function of the local tissue stiffness) was higher at proximal than distal bone regions (p < 0.001).
After suture, the graft bone site was molded with a finger to shape appropriate forms (Fig. 1).
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Currently, different radiographic means are used for preoperative tooth and bone-site and implant-site assessment.
Osteoclasts activity has been shown to be highly variable, depending on bone-site origin [ 40, 41].
This different dynamic of osteoclastogenesis possibly could be, due to the cellular composition of the bone-site specific marrow [ 93].
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