The subchondral bone sclerosis and the bone cysts may be reduced as well, resulting in lower pain and better cartilage repair (Intema et al. 2011; Lamm & Gourdine-Shaw 2009).
Bone sclerosis of the sinus wall is often described.
In summary, articular degeneration and bone sclerosis are the most consistently observed characteristics of osteoarthritis (OA).
Osteoarthritis (OA) is characterized by cartilage damage and loss, synovial membrane inflammation, and bone sclerosis and the formation of osteophytes.
The most common imaging findings of osteosarcoma in the mandible include bone destruction with areas of bone sclerosis, extension to the soft tissues, and an osteoid pattern of tumour matrix mineralisation.
For those sites of bone sclerosis identified on CT, the relative density of sclerosis was intermediate between trabecular and cortical bone; mean (SD) HU for sclerosis was 814 (288), compared with 180 (86) for adjacent trabecular bone and 1,443 (431) for cortical bone, ANOVA P < 0.0001.
So, morphological features of OA include phenotypic changes in chondrocytes, progressive fibrillation of articular cartilage, subchondral bone sclerosis, osteophyte formation, increased remodeling of the periarticular bone and synovial hypertrophy (Li et al. 2013).
The progression of the cartilage lesions is linked together with the subchondral bone sclerosis creating a stiff inelastic tissue [ 6].
Typical for melorheostosis is a presence of bone sclerosis with a linear pattern mainly affecting the cortex of tubular bones which is identifiable by plain radiography [ 3].
Importantly, subchondral bone from OA patients is reported to be undermineralized (31) and may contribute to the subchondral bone sclerosis observed.
