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Actuarial survival curves were plotted from the diagnosis of flat bone sarcoma using the Kaplan Meir method (Kaplan and Meier, 1958; Meyer et al, 1992).
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The first aim of this study was to evaluate the efficacy of combination antiemetic therapy with a 5-HT3RA plus NK-1RA and Dex in patients receiving chemotherapy for high-grade bone and soft tissue sarcoma using multiple HER anticancer agents.
This study demonstrated that consecutive-day granisetron administration was not inferior to single-shot palonosetron for controlling CINV associated with treatment of high-grade bone and soft tissue sarcoma using multiple HER chemotherapies.
Therefore, the gene profile of SP cells might help to expand the possibility of an effective isolation of CSCs from bone and soft tissue sarcomas using these specific markers.
In the field of bone and soft tissue sarcoma, only Wu et al (2007) succeeded in showing the in vivo cancer-initiating ability of CSCs derived from bone and soft tissue sarcomas, using SP cells isolated from fresh primary tumour tissues.
A histological grading of the bone sarcoma was performed according to the grading system proposed by Borders AC [ 15] and a histological evaluation of soft tissue sarcoma was performed using the grading system of the French Federation of Cancer Centers Sarcoma Group system [ 16].
Multivariable linear regression and direct standardisation were used to compare bone sarcoma survivors and the OHLS population.
Today, rotationplasty is mainly used for local disease control in young children with bone sarcoma around the knee (Merkel et al. 1991, Winkelmann 1996).
Open image in new window Fig. 2 Male patient 22 years old with bone sarcoma of the tibia.
He started a registry of bone sarcoma, the forerunner of all cancer registries.
For bone sarcoma, the median age was 44 years; for non-sarcoma patients with soft-tissue tumors it was 53 years, and for non-sarcoma patients with bone tumors it was 47 years.
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