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They found that all of the species, including the red deer Cervus elaphus (right), had LAGs (denoted by arrows in bone sample from the species, left).
"When we exhumed the body in 2010, we took a small bone sample from the nose so that we could examine its chemical composition," project leader Jens Vellev, an archaeologist at Aarhus University in Denmark, said in a statement.
A DNA extraction of a ∼6,000 year-old bone sample from an extinct caprine (Myotragus balearicus) from the Balearic Islands in the Western Mediterranean, has been subjected to shotgun sequencing with the GS FLX 454 platform.
The bone sample from individual 176.3 was analysed for expression of wild-type and mutant IFITM5 mRNA.
RNA was extracted from a bone sample from one patient and Sanger sequenced to determine expression of wild-type and mutant IFITM5.
Unfortunately, accurate quantification of mRNA transcripts could not be performed, as this would require large volumes of bone sample from affected cases.
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Human trabecular bone samples from proximal tibia were harvested from a 71-year old female cadaver with osteoporosis.
Ten bone samples from patients undergoing hip replacement due to osteoarthritis (mean age 80 ± 5) served as controls.
The aim of this study was to investigate gene expression and bone architecture in bone samples derived from elderly osteoporotic women with hip fractures (OP) in comparison to bone samples from age matched women with osteoarthritis of the hip (OA).
Study Design: We microscopically reviewed 5034 maxillofacial bone samples from the Latvala Inflammatory Bone Registry for evidence of heterotopic salivary inclusions within the marrow tissues.
Experiments on human trabecular bone samples from a healthy male donor revealed that failure of such samples is highly localized in fracture bands.
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