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Immobility, causing a reduction in BMD due to increased bone resorption, is a moderate risk factor for fragility fractures, with a relative risk of 1.5 2.
Increased bone resorption is a characteristic of AS [ 19, 20].
Increased bone resorption is a characteristic of AS and RA [ 26- 29].
Bone resorption is a potential issue associated with the retention of a temporary spacer.
Inadequate bone formation following excessive bone resorption is a major cause of age-related bone loss.
Activation of osteoclastic bone resorption is a common factor in the pathogenesis of bone loss and fractures [ 9].
Similar(46)
Bone resorption is an important cellular function in the development and physiology of the skeleton.
These results suggest that osteoclast-driven bone resorption is an important target for treatment of prostate cancer to bone metastasis.
Currently it is believed that bone resorption is an important requisite in the progression of bone metastasis even when a net increase in new bone formations is observed.
Confirming bone resorption is an early local event in OA progression, cathepsin K positive osteoclasts were found invading the articular cartilage from the subchondral region at week 2.
The fact that degradation peptides of type I collagen (N-telopeptide cross-links) and increased levels of deoxypyridinoline and pyridinoline crosslinks can be measured in serum and urine from patients with a loosened total hip arthroplasty indicates that bone resorption is an important part of the pathogenesis of aseptic loosening [ 4, 5].
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