Sentence examples for bone renewal from inspiring English sources

This slowdown of bone renewal can often lead to osteoporosis, a disease in which bones become incredibly fragile, and therefore more susceptible to fracture.

Cell cell communication between cells of the osteoclastic lineage and cells of the osteoblastic lineage is thought to couple resorption and formation so as to preserve bone integrity and achieve homeostatic bone renewal.

In humans, high level of collagen remodeling is seen during normal physiological events such as bone renewal, as well as in pathological conditions, such as arthritis, tumor growth and other chronic wounds.

In this article, we have outlined the deep mechanism of a continually bone renewal practice, called bone remodeling.

In normal bone, homeostasis is maintained and bone integrity is preserved by a continuous cycle of bone renewal.

Understanding how to increase the rate of bone renewal might therefore help scientists develop new treatments for bone diseases.

The realization that ONJ could be the product of the loss of osteoclastic bone remodeling and renewal in the presence of physiological stress, local trauma or tooth infections offers some indications on strategies for preventing it.

As in all bony vertebrates, of course, there is continual renewal of bone throughout life.

The concept of the niche was coined more than 30 years ago to describe the structural and regulatory microenvironment that sustains long-term renewal of bone marrow HSCs (Schofield, 1978).

These data suggest that gene activation and silencing affected by H3-Lys9 andtylation andimethylationon, respectively, may be essential to the maintenance of human bone marrow MSC self-renewal and multi-potency.

Functional analysis revealed that many key cellular pathways in human bone marrow MSC self-renewal, such as the canonical signaling pathways, cell cycle pathways and cytokine related pathways may be regulated by H3-Lys9 modifications.