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The radiologic and histologic results were less favourable with regard to bone remodelling than the results obtained in similar experiments with non-irradiated cortical bone scaffolds.
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Owing to this fact, patients with bone metastases present a higher degree of bone remodelling than healthy individuals, thereby making bone remodelling a useful indicator when diagnosing bone metastases.
Osteoregeneration was more successful in the PRP-additive group, which accumulated bone remodeling than in the other groups.
In particular, at 6 months, test implants (1.72 mm) exhibited a more pronounced bone remodeling than control implants (0.68 mm).
The plain radiographic results of the implants with early rotation did not show any greater incidence of bone remodeling than in those with minimal rotation.
The result of immunohistochemistry staining showed that the HA/PDLLA scaffold had significantly higher infiltration and activation of the bone remodeling process than did the β-TCP scaffold; thus, the HA/PDLLA scaffold indicated a lower risk of residual scaffold.
The decrease in bone mineral density is the consequence of an unbalanced bone remodelling process, with the occurrence of more bone resorption than bone formation.
An important function of bone remodelling is the repair of microcracks accumulating in the bone matrix due to mechanical loading.
b Three-dimensional CT VR reconstruction shows bone remodelling in the supraorbital left area (arrow).
Bone remodelling involves the coordinated effort of osteoclasts and osteoblasts.
This contribution offers an overview of: the growth of bone, peak bone mass, the composition of bone, bone remodelling, the regulation of bone remodelling and resulting bone disease.
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