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Bone relapse was defined as metastases to bone without visceral metastasis.
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Relapse was defined as >5% leukemic cells in bone marrow aspirates or new extramedullary leukemia in patients with a previously documented CR.
Relapse was defined as recurrence of ≥25%% lymphoblasts in bone marrow or local leukemia infiltration sites.
Relapse was defined as more than 10%% leukemic cells in bone marrow aspirates or new extramedullary leukaemia in patients with a previously documented CR.
Relapse was defined by the appearance of circulating blasts or bone marrow blasts >5% in a patient previously in complete remission.
Relapse was defined as an emergence of the disease with ≥25% of blasts in either bone marrow or extramedullary or both.
Isolated CNS relapse was defined as a CNS relapse that was the first event following CR without evidence of bone marrow (BM) or other extramedullary relapse within 30 days [ 10].
Relapse was defined as the presence of at least one of the following: recurrence of>10% leukemic cells in bone marrow or any leukemic cells in peripheral blood or extramedullary sites.
Time to relapse was defined as the time from the date of induction therapy to the date of detected relapse or last clinical follow-up.
Relapse was defined as recurrence of either: 1) papilloedema or 2): symptoms and demonstrated raised intracranial pressure.
Relapse was defined in fifteen patients as a local recurrence of the tumour.
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