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The results revealed that the BM-MSCs endowed β-TCP scaffold with a better and more rapid bone regenerating potential: since the first evaluation period of 2 weeks, the regenerated bone tissue in group I was more mature, denser and homogeneously distributed.
Quercetin-pretreated hADSC showed better bone regenerating ability in skull defect model of nude mice than naive cells.
To further optimize the therapeutic efficacy, the prepared ALN/CUR nanoparticles were decorated with hyaluronic acid which is a well-documented biomacromolecule having exceptional bone regenerating potential.
The objective of this study was to place bone graft materials in cranial defects in a rabbit model and compare their bone regenerating ability according to the size and density of demineralized dentin matrix (DDM).
Since the bone regenerating potential of MAPCs was well reported in previous studies [ 18, 23], our efforts were focused mainly on the materials aspect to compare natural and synthetic components in bone regeneration.
The potential of these scaffolds as bone regenerating material was evaluated by examining the effect of the morphology of sHA and nHA on the adhesion, proliferation, and differentiation of MC3T3 osteoblast cells.
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Human bone regenerates through patterns of maturation similar to those of bone growth in response to bone defects of any cause.
Preferential alignment of the BAp c-axis in the rabbit ulna and skull bone, regenerated by controlled release of basic fibroblast growth factor (bFGF) was investigated.
The cumulative results for mineralization of the bone regenerates in comparison with the underlying basal bone of the skull showed independently from the technique applied no difference bigger than 5%.
This idea has long been used to inform orthopaedic practice, and it is in this tradition that we here address an open question in human bone biology: where, precisely, is bone regenerated in response to osteoporosis therapy?
In contrast, dexamethasone tended to increase the mechanical strength of metaphyseal bone regenerated under stable conditions.
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