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Bone recurrence was defined as bone metastasis detected as the first site of recurrence after esophagectomy or detected within 1 month of first site of recurrence after esophagectomy [ 7, 13].
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A recurrence was defined as any local (chest wall) or systemic (visceral or bone metastasis) recurrence during the follow-up period.
Distant disease recurrence was defined as distant lymph node sites or involvement of distant organs including lung, liver, bone, and subcutaneous tissue.
Clinical recurrence was defined as the development of a biopsy proven local relapse or any lymph node, bone, or visceral metastasis shown to progress on imaging.
Recurrence was defined as tumor regrowth, determined by any cytologic or histologic proof, unequivocal radiologic suspicion (CT, MRI, PET, bone scan, and ultrasonography), and/or obvious clinical manifestations.
Recurrence was defined as a positive finding on a blood test for a substance called prostate specific antigen, or P.S.A.
Recurrence was defined according to protocol.
Recurrence was defined as distant recurrence.
Early recurrence was defined as recurrence within 1 year.
Local recurrence was defined as tumor recurrence in the anus.
Local recurrence was defined as primary tumor recurrence, and regional recurrence was defined as recurrence in the mediastinum, hilum and supraclavicular fossa.
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