Exact(2)
Orth et al. [ 15] found that articular cartilage repair and subchondral bone reconstitution proceed at a different pace and that the advancement of the subchondral bone plate was not related to the diminished articular cartilage repair in a rabbit model of spontaneous osteochondral repair over a one-year period.
However, Orth et al. [ 15] found that articular cartilage repair and subchondral bone reconstitution proceeded at a different pace and the advancement of the subchondral bone plate was not related to the diminished articular cartilage repair in rabbit spontaneous osteochondral repair model over a one-year period.
Similar(58)
Bone marrow reconstitution experiments demonstrated that the MZB cell phenotype of SIRPα MT mice was due to lack of SIRPα signaling in non-hematopoietic cells.
Similarly, a recovery period should also be considered after imaging, depending on the type of anaesthetic, the length of anaesthesia and experimental procedures carried out (e.g. significant blood volume withdrawal, surgically induced procedure, bone marrow reconstitution).
In addition, the bone marrow reconstitution in human patients with severe combined immunodeficiency (SCID) due to mutation of the gene encoding the common γ chain cytokine receptor subunit IL-2Rγ or the tyrosine kinase JAK3 did not restore presence of ILCs in various peripheral tissues (Vely et al., 2016), supporting the notion that tissue-resident ILCs are established at early ontogenic stages.
Although there were no significant differences in the immunophenotypic hematopoietic stem and progenitor cell (HSPC) populations between Col1a1-Cre+/COMP-Angpt1+ and control mice, lineage−Sca-1+c-Kit+ (LSK) cells isolated from 8 wk-old Col1a1-Cre+/COMP-Angpt1+ mice showed better long-term bone marrow reconstitution ability.
Bone marrow reconstitution was verified by flow cytometric analyses.
Using bone marrow reconstitution analysis, we showed that the tumor stroma also contained functional hematopoietic stem cells.
Ten to twelve weeks after bone marrow reconstitution the mice were sacrificed and analyzed by flow cytometry.
Bone marrow reconstitution is classically used to separate the effects on lymphoid organogenesis from the functional defects in adult mice.
Chimeric mice were generated by bone marrow reconstitution of irradiated C57BL/6 or lymphotoxin-α knockout (LT-α KO) mice that had been splenectomized 3 to 4 weeks earlier.
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