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The reambulation period in this study was relatively short and at its completion, trabecular bone quantity of the mechanically stimulated mice was still lower compared to age-matched controls.
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For analysis of bone quantity, the area and bone mineral density of cortical bone were evaluated using peripheral quantitative computed tomography (pQCT), while the orientation of the BAp c-axis, as analyzed by a micro-beam X-ray diffraction system, was used to assess bone quality.
Similarly, the determination of bone quality is of equal importance as bone quantity when assessing the efficacies of new therapeutic agents.
The limitations of assessing bone quantity with the BMD have been discussed previously.
The primary stability is affected by the implant design, including surface-modifying or implant cavity-forming techniques, as well as by the bone quantity and bone density of the patient [1 3].
These BMP-2 induced bone quantities come into the range of the new bone formation using PCL noncoated or PCL coll I/cs coated scaffolds without any growth factor application, indicating that the PCL scaffold by itself acts beyond osteoconductive properties.
However, VEGF specifically caused a global reduction in bone quantity, which consisted of thin trabeculae of immature matrix.
Measurements of bone mineralization provide a valuable estimation of bone quantity and quality that correlates to biomechanical properties, but the technique cannot accurately predict biomechanical competence [ 16].
Bone mineral density (BMD), which measures the quantity of the calcified bone, at present is the gold standard technique for the diagnosis of osteopenia and osteoporosis.
The results of both bone quantity and quality assessments indicated that changes during bone growth varied depending on the presence of teeth.
We tested the response of MAT to high fat diet (HFD) and exercise using a novel volumetric analysis, and compared it to measures of bone quantity.
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