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Moreover, trabecular bone parameters in the tibia were analyzed by micro-computed tomography (μCT).
There were good correlations between body weight and bone parameters in the femur and tibia.
Detailed analysis of the trabecular bone parameters in the 13-week old female mice revealed interesting site-specific responses to Lef1 haploinsufficiency.
The two apparently mechanistically different bone phenotypes in Per2- or Cry2-deficient female mice and the previously described non-allelic compensation of the different chrono-phenotypes that these animals display [8] lead us to investigate bone parameters in the Per2Brdm1/Cry2−/− double mutant mice.
This study extends the literature that uses in HR pQCT to examine "bone quality" in vivo in a novel way using customized image acquisition and analyses protocols to assess bone parameters in the distal forearm and hand.
In order to justify the use of the contralateral knee as control, we calculated bone parameters in the diaphyseal and metaphyseal tibia, distal from the joint, containing cortical and trabecular bone, respectively.
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On the other hand, as reported in the present study, after 8 weeks of cessation of jumping exercise in 8J8S, there were no significant differences in the measured bone parameters in this group of rats as compared to the control rats.
Irrespective of sex effects, our data indicate that body weight did not affect any of the analyzed bone parameters in this animal sample (Pearson's r ≤ 0.11).
Several studies have looked at the association between trace-element intake and bone parameters, in addition to the possible benefits of supplementation with trace elements.
Therefore, although during the follow-up, DXA may show stable values, the other methods may indicate the contrary: a decrease of bone parameters in some JIA subgroups, thus better reflecting the evaluation of skeletal status.
Variables related to growth (age, height, and pubertal maturation) are independent positive predictors for the bone parameters in both boys and girls.
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