Sentence examples for bone microenvironment was demonstrated from inspiring English sources
The importance of interactions between tumor cells and other cells in the bone microenvironment was demonstrated in the 1990s by the work of Dr. Greg Mundy and others in the field.
The aging microenvironment was demonstrated to have an inhibitory effect on adult stem cells [ 41– 41].
The ability of HA to affect breast cancer cell colonization and tumor growth within the bone microenvironment was next assessed.
High osteolytic activity of the 4 T1.2 lucellslls in vivo in the bone microenvironment was also detected.
Collectively our observations indicate that the cortical bone microenvironment was affected by the exercise stimulus and responded accordingly.
Some recent studies have demonstrated that cross-talk within the bone microenvironment is not limited to bone cell lineages; in fact, other cells of the immune system may be involved in the regulation of bone homeostasis, such as a particular population of resident tissue macrophages.
It is also unknown whether ligands in the bone microenvironment are subjected to change in different physiological conditions.
Moreover, the bone microenvironment is known to support tumor growth in leukemia, myeloma and solid tumor bone metastasis [10], [11], [12], [13].
Recently, other cells of the bone microenvironment are emerging as implicated in bone health.
In vivo models that mimic the breast cancer-specific osteolytic bone microenvironment are limited.
