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It is a generally accepted hypothesis that fluid flow within the bone matrix plays a key role in a strain-sensing mechanism involved in the normal adaptive response of bone (Van der Vis et al. 1998a, b, Skripitz and Aspenberg 2000, Qin et al. 2002, Astrand et al. 2003).
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The bone matrix plays an important role in the response to physical stress.
The extracellular matrix plays an important role in tissue regeneration.
OPN is a major cell- and hydroxyapatite-binding protein synthesized by osteoblasts; it is involved in anchoring osteoclasts to the mineral of bone matrix, and it plays a critical role in bone remodeling [ 25, 26].
Osteopontin is a major non-collagenous bone matrix protein that plays an important role in bone formation and resorption.
It is present in bone matrix and it plays an important role in the initial vascularization for the endochondral bone formation [ 9, 10].
Bone vasculature plays a vital role in bone development, remodeling and homeostasis.
As Neo's theme from The Matrix plays, Snowden swaggers into the ring holding a Rubik's cube.
Developed as an artificial bone matrix, a tissue engineering scaffold plays an essential role in regenerating bone tissue.
Bone tunnel enlargement plays an important role in revision surgery.
Matrix metallopeptidase 2 (Mmplayslays a key role in matrix turnover (Stamenkovic 2003).
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