Your English writing platform
Discover LudwigExact(8)
After birth, bone mass increases until it reaches "peak bone mass", which is then maintained at a constant level during young adulthood, followed by an age-related bone loss [16].
Only the peak bone mass, which is the maximum bone mass, is markedly higher in men than in women [ 39].
This dysregulation causes reduced bone mass, which is known to be an early feature in RA patients, visualised as juxta-articular bone demineralisation on radiographs [ 3].
The development of postmenopausal osteoporosis is determined by the size of the peak bone mass, which is defined as the highest bone mass achieved during life.
Peak bone mass, which is reached by early adulthood, serves as a bone reserve for the remainder of life, therefore childhood and adolescence are crucial periods for bone development.
Similar to peak bone mass, which is a strong predictor of future risk of osteoporosis in older people [ 30], peak cartilage volume in a younger age group should be protective against the development of OA in later life.
Similar(52)
A logistic regression model was used to estimate the odds ratio of different variables forlow bone mass, which was considered as the dependent variable.
As expected, OVX rats treated with E2 for 12 weeks ameliorated the loss of bone mass, which was reflected by the increased TBV% and the decreased levels of TRS%, TFS%, MAR, OSW, and mAR.
Body mass index is also associated with both lean and fat body mass, which are also predictors of bone mineral content[ 35].
Thus, a deficient imbalance in bone mass in relation to muscle mass (which is a surrogate for muscle strength) during AN, may be the cause of an increased bone fragility in later life [ 77].
Although galectin-8 can potentially bind to receptors that both negatively (LRP1) and positively (MRC2 and uPAR) regulate RANKL expression, the net effect is still an increase in RANKL expression and reduction in bone mass, which could be attributed, for example, to different expression levels of these receptors in osteoblasts.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com