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Peak bone mass is achieved by men and women in the middle of the third decade of life.
Once the peak bone mass is achieved, strategies to minimize bone loss should also be included.
In healthy adults maintenance of bone mass is achieved by coupling of bone formation and bone resorption processes [ 1].
Peak bone mass is achieved soon after puberty, and bone is lost with various "insults", including ageing and postmenopausal changes.
Male C57BL/6 mice (n = 62, Charles River, Wilmington, MA) were obtained at 8 weeks of age and housed until 16 weeks of age, at which time active growth has decreased, and peak bone mass is achieved [ 33, 34].
In fact, when peak bone mass is achieved, bone density in men is one fourth to one third greater than in women [ 15] and male bones reach a larger diameter and cortical thickness than female ones [ 15, 18].
Similar(53)
The male PRKO mice had 23% higher cancellous bone mass when compared to the WT when the peak bone mass was achieved at six-month of age.
We speculate that this inhibition of stature when young results in a lower peak bone mass being achieved, thus predisposing to osteoporosis in later life.
Premature birth results in lower attainment of height achieved by young adult age but bone mass is appropriate for body size.
Nearly 40percentt of peak bone mass is accumulated during adolescence.
Bone mass is maintained by continuous remodeling through repeated cycles of bone resorption by osteoclasts and bone formation by osteoblasts.
More suggestions(18)
bone mass is established
bone mass is characterised
bone mass is produced
bone health is achieved
bone healing is achieved
bone mass is underscored
bone mass is correlated
bone graft is achieved
bone augmentation is achieved
bone mass is determined
bone density is achieved
bone mass is accumulated
bone mass is observed
bone length is achieved
bone bed is achieved
bone mass is maintained
bone formation is achieved
bone mass is developed
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Justyna Jupowicz-Kozak
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