Sentence examples for bone mass has been from inspiring English sources
Once peak bone mass has been reached, further gains are minimal, so childhood through adolescence is the best time to pay attention to bone development.
Clinically, osteopenia or low bone mass has been observed in a variety of chronic inflammatory diseases, and elevated proinflammatory mediators have implicated this process.
A reciprocal association between bone marrow fat and bone mass has been reported in ovariectomized rodents, suggesting that bone marrow adipogenesis has a negative effect on bone growth and turnover balance.
In children after fractures, a decrease in bone mass has been demonstrated in the injured limb [16].
For instance, decreased bone mass has been shown to be present in children suffering from cerebral palsy or chronic neuromuscular disorders [12 14].
The second evaluation was performed at 12 weeks of age (three months), which is a post-pubertal time point when the peak bone mass has been mostly achieved, bone mass acquisition has slowed, and the mouse reproductive system is fully developed.
However, the results on bone mass have been inconsistent.
The effects of treadmill exercise on bone mass have been studied extensively, but there is a lack of evidence about its influence on articular cartilage change.
More direct roles for Wnt signalling in the reduction of trabecular bone formation and bone mass have been shown in studies of mice lacking the soluble Wnt inhibitor sFRP1, with the mice demonstrating reduced osteoblast and osteocyte apoptosis [ 28].
Ovariectomy (Ovx) alone has been demonstrated to induce a significant decrease of bone mass density in sheep[ 8, 9] but the changes in the bone mass have been observed directly after Ovx only and no long-term effect was found [ 10].
However, although gender differences with respect to bone mass have been shown for example [ 16], it is likely that this diversion between males and females is more related to the differing overall distribution of soft tissues, for example, adipose and muscle, in the body between males and females [ 11].
