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Another aspect is the possible difference in the kinetics of the radiopharmaceutical in the low uptake compartment compared to the bone marrow, which may lead to an overestimation or underestimation of the absorbed dose to the bone marrow using a fixed ratio.
CD248 is also expressed in human mesenchymal stem cells from bone marrow, which may differentiate into tumor stromal fibroblasts [ 22].
Technique 2 causes certain interpretation difficulties, particularly when benign lymphocytic aggregates are present in the bone marrow, which may appear in both normal bone marrow and bone marrow affected by inflammatory process.
Thus, it seems plausible that the production and release of cytokines, chemokines and proteolytic enzymes (VEGF, SDF-1 and metalloproteases) by the lung tumour tissue will increase the mobilisation of CD133+/HPCs from the bone marrow, which may be home to hypoxic tumour tissue and have a fundamental role in tumour neovascularization and progression (Kerbel, 2008; Shojaei and Ferrara, 2008).
These differences may be explained by different local environments such as bone marrow, which may promote proliferation, possibly because of pressure or vascularity differences, growth factors, or some combination thereof or, perhaps, as some authors contend, these lesions arise de novo as notochordal-type tissue expressing markers like brachyury [ 10, 21, 22, 25].
Similar(55)
Bone contains marrow, which may harbor prions, but the removal of the vertebrae of older cattle should lower the risk.
Roberts' disease involves damaged bone marrow, which carries a high risk of developing into leukemia.
This is because of the balance between any possible effects on tumour metabolism (such as macrophage impairment) and systemic effects (such as bone marrow activation following bone marrow depression, which may or may not be caused by growth factors).
This is because of any possible effects on tumour metabolism (such as macrophage impairment) and systemic effects (such as bone marrow activation following bone marrow depression, which may or may not be caused by growth factors).
Diffuse bone marrow involvement, which may or may not be associated with bone destruction, is not evaluable using conventional radiography.
Our orthogonal cutting experiments showed that a rake angle of 60° and a depth of cut of 1 mm, will avoid excessive fragmentation, keep specific cutting energy low and promote bone marrow extrusion, which may be beneficial for cell survival.
Related(19)
bone length which may
bone formation which may
bone strengthening which may
bone metastasis which may
bone mineral which may
bone density which may
bone grafting which may
bone metabolism which may
bone resorption which may
bone stock which may
bone quality which may
bone cement which may
bone thickness which may
bone milieu which may
bone loss which may
bone tissue which may
bone microenvironment which may
bone mass which may
bone health which may
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