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In patients with advanced hematologic malignancies, it is difficult to fully evaluate the hematopoietic toxicity of 5-AZA-CdR due to the presence of a large number of abnormal cells in the bone marrow, which can interfere with recovery after chemotherapy.
Bone marrow transplantationHigh doses of chemotherapy or radiation destroy not only cancer cells but also bone marrow, which is rich in blood-forming stem cells.
Roberts' disease involves damaged bone marrow, which carries a high risk of developing into leukemia.
Members also raised funds for a three-year old's bone marrow transplant, which saved the child's life.
After consultation with Forman, the Hernandez family decided against a standard bone marrow transplant, which uses marrow from a donor.
We observed greater toxicity to bone marrow cells with inhibitors that interfere with the utilization of AA in contrast to those which block utilization of its downstream metabolites.
He had severe bone marrow failure and gut damage, which fitted.
Leukemia is a disorder of the blood cells, which form in the bone marrow.
Thus, Hdac3 depletion in osterix-expressing progenitor cells interferes with bone formation and promotes bone marrow adipocyte differentiation.
Normal bone marrow cells from mice were then exposed to the virus, which transferred the gene into the marrow cells.
De Lisio M, Baker JM, Parise G. Exercise promotes bone marrow cell survival and recipient reconstitution post-bone marrow transplantation, which is associated with increased survival.
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