Sentence examples for bone marrow stroma was from inspiring English sources
Bone marrow stroma was pretreated daily with the different statins.
Bone marrow stroma was cultured from female human ribs removed during routine surgery, after informed consent, for nonmalignant renal disease.
Bone marrow stroma was cultured from human ribs removed for access during routine renal surgery after informed consent (ProMPT LREC 02/ST/122) and prepared for tissue culture using the method of (Coutinho et al, 1993).
In MDS, the adherent layer of bone marrow stroma is defective in supporting normal myelopoiesis in vitro, presenting a poor maintenance of hematopoietic stem cells [ 11].
Prostate cancers ability to invade and grow in bone marrow stroma is thought to be due in part to degradative enzymes.
Macrophages, an important cell-type of the bone marrow stroma, are possible targets of benzene toxicity because they contain relatively large amounts of prostaglandin H synthase (PHS), which is capable of metabolizing phenolic compounds to reactive species.
The adhesion between myeloma cells and the bone marrow stroma is critical for myeloma development, as targeting of VLA-4 with a monoclonal antibody after the establishment of disease in a myeloma mouse model results in decreased tumour cell burden.
Also, since adhesion to bone marrow stroma is associated with chemotherapy resistance, thalidomide and lenalidomide therapy might theoretically make previously chemotherapy-resistant tumours sensitive by affecting stromal myeloma cell interactions.
Bone marrow stroma is the most resistant component of immune system, which can survive exposure to level as high as 15 – 17 Gy, although functional alterations can be observed at lower doses.
The most HA-rich regions of the bone marrow stroma are the endosteum and the sinusoidal endothelium, the sites that are considered the niches of the most primitive HSC.
