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Flow cytometry analysis of bone marrow samples showed no difference in cell composition and maturation before and after CBP.
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A bone marrow sample showed a hyporegenerative state.
PBSC: peripheral blood stem cells; BM: bone marrow samples Significantly, SEMA3A shows up-regulation in patients with t-AML (Q-value = 1.1e-9, FC = 2.3, Figure 2A), even in patients with deletion of chromosome 7 or loss of chromosome 7q (FC = 2.2, Q-value = 4.6e-5, Figure 2B).
However, normal bone marrow samples (n = 5) showed no expression of AQP5 (Figure 1C).
Repeat bone marrow samples were collected, which showed macrophage inclusions consistent with hemolysis.
Retrospective analysis of the presence of EZH2 mutations in archived MPN bone marrow samples has not been shown to have prognostic significance in PMF patients (Abdel-Wahab et al. 2010b).
LGL cells typically express CD57 on their surface and IHC staining showed that bone marrow samples from LGL leukemia patients were infiltrated with CD57-expressing LGL cells, whereas no such infiltration was observed in bone marrow samples from healthy controls.
In group 2, 19 of 24 bursa tissue samples, two bone marrow samples, a thymus sample and four bursa swab samples showed positive results.
CD38bright+ plasma cells in fresh multiple myeloma (MM) bone marrow (BM) samples showed weaker 67LR expression, but expression increased after direct exposure to a BM endothelial cell line (4LHBMEC).
One of the three available bone marrow samples from the p80HT mice with plasma cell tumors showed an excess of bone marrow plasma cells.
These samples showed normal levels of Ki-67+ proliferating Ki-67+ proliferatingwith normal bone marrow samples.
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