For 15 cases bone marrow samples were available.
Paired peripheral blood and bone marrow samples were available at diagnosis in a subset of 56 patients.
Progenitor cell apoptosis was assessed in 34 patients, and bone marrow samples were available for 20 patients.
However, a possible local effect around clusters of myeloid blasts in bone marrow cannot be excluded, as no bone marrow samples were available for analyses in the present study.
However, of the previously published case neither detailed information on clinical findings nor on collected blood nor bone marrow samples were available and therefore documented in the current case report.
In 84 patients, paired blood and bone marrow samples were also available after chemotherapy.
Unfortunately, no pretreatment bone marrow sample was available for LCDD-02.
One of the three available bone marrow samples from the p80HT mice with plasma cell tumors showed an excess of bone marrow plasma cells.
For patients with sufficient material available, pretreatment bone marrow samples were used for DNA and total RNA extraction using TRIzol Life Technologiess, Grand Island, NY, USA) according to the manufacturer's protocol with minor modifications.
A total of 19 paraffin-embedded bone marrow samples (range 1 7 samples per patient; median two samples per patient) from six patients was available.
The complete list of selected samples is available in Table 3. Acute Myeloid Leukemia Dataset (AML): peripheral-blood samples or bone marrow samples of intermediate-risk AML with a normal karyotype [ 35].
