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Scientists have found that cells from the bone marrow play an essential role in building the blood supply on which tumors depend.
Furthermore, MSCs in bone marrow play important role in regulating haematopoiesis [ 19, 20].
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Bone marrow plays an important role in the immune system, and also in bodily rejuvenation.
Bone marrow plays an important role in the immune system and in bodily rejuvenation.
Because many radionuclides lodge for long periods of time in bone, and because bone marrow plays a critical role in immune system function, there are concerns that these substances could cause immune system damage.
MCP-1, a cytokine existing in bone marrow, plays an important role in promoting the activation of monocytes/macrophages and causing the cells to gather in the region of bone damage.
Recent data indicate that bone marrow plays an important role not only as a primary lymphoid organ responsible for haemopoiesis, but also as a secondary lymphoid organ with capability of antigen presentation exceeding that of lymph nodes.
11, 13 As mentioned above, the microenvironment of the lymph nodes and bone marrow plays an important role in the pathogenesis of CLL by promoting further proliferation and survival.
Platelets are anuclear cellular fragments derived from megakaryocytes in the bone marrow and play a crucial role in regulating blood hemostasis.
Evidence suggests that protease release by neutrophils in the bone marrow may play a role.
Immature B-cell lymphocytes are cells from the bone marrow that play an important role in the adaptive immune system.
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