Your English writing platform
Discover LudwigSuggestions(5)
Exact(7)
Bone marrow plasma from all these MM patients suppressed the development of mineralized nodules (Figure 3B).
Treatment with SB431542 restored and enhanced the mineralization suppressed by the bone marrow plasma from MM patients.
The TGF-β inhibition was able to restore OB differentiation suppressed by MM cell conditioned medium as well as bone marrow plasma from MM patients.
Interestingly, a blockade of TGF-β antagonized the suppressive effects of MM cell conditioned media (Figure 3A) and bone marrow plasma from MM patients (Figure 3B), and was able to release stromal cells from differentiation arrest to achieve terminal OB differentiation.
Measurements of soluble endoglin and BMP-9 in bone marrow plasma from 16 myeloma patients showed presence of both soluble endoglin (median 14.1 ng/ml, range 9 22) and BMP-9 (median 33.9 pg/ml, range 5 160).
In addition, there is a tendency (although not statistically significant, P = 0.08) for elevated levels of IL-15 in bone marrow plasma from RA in comparison with OA patients (2390 ± 1687 pg/ml and 1292 ± 457 pg/ml, respectively).
Similar(53)
The current study was designed to determine the expression of CXCR3 on four multiple myeloma (MM) cell lines and bone marrow plasma cells from 20 MM patients.
We next used published gene expression profiling (GSM6477 in GEO)[30] to study EEF1A2 transcript levels in sort-purified CD138+ bone marrow plasma cells from 15 normal controls, 22 patients with MGUS and 125 primary cases of MM (Figure 2A).
To further investigate the effects of TGF-β inhibition on OB differentiation in the context of the MM bone marrow microenvironment, we looked at the effect of TGF-β inhibition on the formation of mineralized nodules in the presence of bone marrow plasma collected from three MM patients with extensive bone destruction.
Bone marrow plasma samples from 16 patients were also obtained as described.
To compare the levels of RANKL, OPG, IL-6, sIL-6R and sgp130 in bone marrow plasma isolated from rheumatoid arthritis (RA) and osteoarthritis (OA) patients.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com