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There was no microscopically detectable bone marrow involvement by germ cell tumour cells in these two patients (Table 3-wrap>).
10 The extent of bone marrow involvement by lymphoma and the pre-treatment platelet counts correlate with the risk of myelosuppression.
Scintigraphic assessment of absorbed dose to the bone marrow has its shortcomings owing to over- and underlying tissues as well as to the local variability in bone marrow involvement by the disease targeted.
Eligible patients were aged ≥18 years, with histologically confirmed DLBCL that had relapsed or was refractory after one prior therapeutic treatment, and had either measurable disease or confirmed bone marrow involvement by DLBCL without measurable disease.
The maximum tolerated total body dose has been established at 75 cGy in patients with adequate bone marrow reserves and less than 25% bone marrow involvement by lymphoma, 65 cGy in patients with mild thrombocytopenia, and 45 cGy in patients who have received stem cell transplantation [ 77].
WM is defined by the presence of a monoclonal IgM (M spike) of any degree, more than 10% bone marrow involvement by a lymphoplasmacytic infiltrate, and presence of end organ damage directly attributable to either the B-cell clone or the M protein.
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Bone and bone marrow involvement is unusual.
Among these latter cases, one-third account for bone marrow involvement undetected by PET.
MRI, however, is usually the best imaging system for the evaluation of a soft-tissue mass or the extent of soft-tissue or bone-marrow involvement by a bone tumor [ 2].
Bone marrow involvement was defined by bone marrow aspiration and/or biopsy with a dense focal or diffuse mast cell infiltrate with spindle-shaped cells [15].
Bone marrow involvement was assessed by an aspiration and bone marrow biopsy from iliac crest.
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