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– Inadequate bone marrow function to undergo planned therapy.
Prior to therapy administration, patients are screened for adequate renal function, hepatic function, and bone marrow function to ensure these acute side-effects are resolved.
Similar(58)
Further, elderly patients have poorer bone marrow function compared to younger patients and also seem to be more vulnerable to infectious diseases.
Patients were also required to have adequate renal, hepatic, cardiac and bone marrow function and to be on stable or decreasing dose of steroids in the 2 weeks prior to enrolment.
All patients were required to have a normal hematological profile and adequate liver, kidney, and bone marrow function, and to have recovered from any therapy-related toxicity from previous chemo-, hormone-, immuno- or radiotherapies.
Adequate bone marrow function was to be documented with neutrophils ⩾1.5 × 10 l−1 and platelets ⩾100 × 10 l−10
Declining bone marrow function continues to be a common event during the course of prostate cancer with skeletal metastases.
In addition, patients had to be 18 75 years old, have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 2, have adequate liver, kidney, and bone marrow function, and to have received no prior treatment with capecitabine or platinum compounds.
The M/E ratio is relevant to bone marrow function and also to diseases of bone marrow and peripheral blood such as leukemia and anemia.
We suggest that cytopenias, the detection of which constitute pillars of the diagnostic algorithm of SLE, are the consequence of abnormal bone marrow function, in addition to specific antibody mediated direct damage.
Eligibility also required adequate renal, hepatic and bone marrow function, no previous exposure to chemotherapy or radiotherapy, and no prior or concomitant malignancy.
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