Sentence examples for bone marrow compartments from inspiring English sources
Twenty-four hours after the final administrations, dose-related micronucleus responses were evident for both agents and in both blood and bone marrow compartments.
However, STAT6-independent IL-5-regulated eosinophilic pathways operate in blood and bone marrow compartments.
Our results suggest that PECAM-1 plays an important role in integrating CXCL12 dependent signals involved in HSC accumulation within the bone marrow, such that loss of PECAM-1 preffectivefective bidirectional movement of HSCs between the blood and bone marrow compartments.
For this purpose we initialized all bone marrow compartments with 1% and GRA with 50% of their equilibrium values.
The model of chemotherapy is based on transient cell depletions of bone marrow compartments in dependence on drugs and drug doses.
A major challenge of our approach was to substitute the feedback-loop signaling from more mature bone marrow compartments back to stem cells.
Moreover, 18F-FLT PET/CT was characterized by high background activity in the bone marrow compartment, further complicating the evaluation of bone marrow lesions.
Bone marrow failure syndromes (BMFS) typically present with a marked reduction of peripheral blood cells due to a destroyed or dysfunctional bone marrow compartment.
Interestingly, two patients with the initial diagnosis of SMM demonstrated focal bone marrow lesions and were classified as symptomatic MM. 18F-FLT PET/CT was characterized by high background activity in the bone marrow compartment (Fig. 2).
Another finding of our analysis is the high background 18F-FLT activity in the bone marrow compartment, which further complicates the evaluation of bone marrow lesions in 18F-FLT PET/CT.
We predict that the ability to tissue engineer a morphologically intact and functional large-volume bone organ with a humanized bone marrow compartment will help to further elucidate physiological or pathological interactions between human HSCs and their native niches.
