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Modic changes (MC) are vertebral subchondral bone marrow changes that are visible in magnetic resonance imaging (MRI).
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The sensitivity of MRI for soft tissue assessments and bone marrow changes exceeds that of conventional radiographs.
Besides bone marrow changes, evidence has shown that apoptosis is involved in the early stages of steroid-induced osteonecrosis [ 26].
Thus, it appears that bone marrow changes can be suppressed (by about 5%) by pravastatin treatment.
Imaging studies have shown that bone marrow changes occur in patients with rheumatoid arthritis (RA).
Evidence has accumulated over the years that bone marrow changes in RA also involve the subchondral bone marrow of peripheral joints [ 71].
Please note that type 2 degenerative bone marrow changes at L5 S1 and L3 L4 do not demonstrate the claw sign.
Our study suggests that the microenvironment of the bone marrow changes in patients who progress to bone marrow involvement.
Therefore, it is unlikely that these calves would have shown any bone marrow changes.
Chronic axial compression of the mouse tail segment induces MRI bone marrow edema changes that correlate with increased marrow vasculature and cellularity.
It was the reserve area of bone marrow that was changed, depriving the infection of a critical source of re-infection, thus allowing the immune system to clear the virus summarily from the "open" target cells.
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