These mice had meanwhile been irradiated to destroy bone marrow cells and would have died without the new cells.
In addition to being one of the first to report on the cancer-inducing effects of radiation exposure, he studied its effects on bone marrow cells and developed a method of treating leukemia.
Co-injection of engineered Tregs with donor bone marrow cells and splenocytes prevented recipients from lethal GVHD.
They exhibited moderate clastogenicity, low antiproliferative activity on mice bone marrow cells and well expressed cytotoxicity against human tumor cell lines.
In co-cultures of mouse bone marrow cells and osteoblasts, a TLR2/6 ligand (diacylated lipopeptide designed from Gram-positive bacteria) markedly induced osteoclast formation.
We previously investigated whether dental pulp-derived cells possess similar pluripotency to bone marrow cells, and reported their capacity to differentiate into osteoblasts, as well as the characteristics of the stem cells present in dental pulp.
The influence of five different controlled- and noncontrolled-rate cryopreservation protocols combined with different DMSO concentrations was assessed on the recovery of frozen mouse bone marrow cells and human peripheral blood mononuclear cells (MNC).
We observed that BPA exposure caused a significant increase in the frequency of micronucleus (MN) in polychromatic erythrocytes (PCEs), structural chromosome aberrations in bone marrow cells and DNA damage in blood lymphocytes.
After irradiating mice to kill most of their bone marrow cells and create a vacancy that new cells might occupy, the researchers injected the neural stem cells into the animals.
Dr. Abedi provided animals, sorted bone marrow cells and transplanted cells into animals.
Next, we isolated bone marrow cells and cultured the cells under osteoblast differentiation conditions.
