Sentence examples for bone marrow cell models from inspiring English sources
As described [1], [6], [7], [8], [9], [11], bone marrow cell models in vivo and in vitro including ours [18], all support a model in which adipocytes form at the expense of osteoblasts, which may be processed at least in part by the PPARγ-mediated downregulation of Runx2 [28], [28].
The combination of benzopyrene, a tobacco smoke aryl hydrocarbon, and P. gingivalis lipopolysaccharide (LPS) significantly increase the inhibition of osteogenesis in a rat bone marrow cell model compared to either agonist alone [13].
Consistently, although Nishida et al. [ 26] found markedly reduced total bone marrow cell numbers in a murine CIA model which is similar to patients with RA [ 27], the proportion of cells from the myeloid lineage was found to be elevated in murine arthritis models [ 6, 28].
The top 10 instances sharing the largest number of significantly affected GOMs with bone marrow cells form hypoxia model are listed in A and the top 10 instances resulted from distance comparison method are listed in B. Detailed parameter settings: GO mode: BP; P-value: < 0.05.
The results indicated that there is redundancy in pathogenic TNF sources (bone marrow cells in the TNFΔARE model or stromal-radioresistant cells in the Tg197 hTNF+/- model) that suffice for the induction of arthritis.
Insulin producing cells were also reprogrammed from circulating bone marrow cells in a rat model by repressing Sonic Hedgehog and Rest/Nerf, and expressing the 'pancreatic' transcription factor Pdx1 (Li et al, 2012).
In one model, bone marrow cells were retrovirally transduced with a construct, encoding the activating intracellular Notch1 domain.
Characterization of Recql4HD mice showed that dysfunction of Recql4 in vivo causes sparser tail hair and fewer blood cells, a phenotype that may be attributed to higher senescence of hair follicles and bone marrow cells, respectively, in this mouse model.
Bone marrow cells showed therapeutic efficacy in a model of brain injury known to promote low structural plasticity.
Unlike in the present study, these authors used mice deficient in the low-density lipoprotein receptor that were transplanted with Nlrp3-, Asc- or IL-1α/β-deficient bone marrow cells after lethal irradiation as a model of atherosclerosis.
