55 Bone marrow‐derived DC can activate NK cells through the TICAM‐1 pathway in polyI C‐stimulated DC. 56 Bone marrow‐derived DC drive antitumor NK cytotoxicity, depending on the TICAM‐1 pathway.
The release of glutamate from MKs provides a cellular source of glutamate within the bone marrow compartment, which can potentially activate their NMDA glutamate receptors in an autocrine fashion controlling megakarocytopoiesis and platelet production.
Bone marrow transplantation can successfully treat some of those diseases.
Bone marrow transplants can also confound forensic scientists.
Bone marrow oedema can be visible on STIR imaging.
After leaving the bone marrow, IgM positive B cells can be activated by antigen and enter a germinal center in lymphoid tissue.
TOLERIN treatment prevented sepsis and activated bone marrow function in these patients.
RD-LPS treatment prevented sepsis and activated the bone marrow function in these patients.
Mechanistically, bone marrow transplant experiments demonstrate that TBI activates p53 to decrease the ability of bone marrow cells to suppress lymphoma development through a non-cell-autonomous mechanism.
Cancers such as leukemia and a few genetic conditions can weaken the bone marrow, necessitating a bone marrow transplant.
