Sentence examples for bone markers such as from inspiring English sources

Differentiation was evaluated by scanning electron microscopy, whereas the expression of bone markers such as ALP, Osteocalcin, COLL1 and Osteonectin was investigated by quantitative real time polymerase chain reaction (qRT-PCR).

Although protein level down-regulation of bone markers, such as osteocalcin, would be useful, this work has not yet been undertaken.

Bone markers such as total and bone-specific alkaline phosphatase may need to be used as surrogates for response to cabozantinib; however, these are nonspecific and could be affected by other bone-targeted therapies such as zoledronate or denosumab.

Another limitation is the lack of data on bone markers, such as the RANKL/osteoprotegerin ratio and bone and cartilage markers (CTX-1 and -2), which independently predict radiographic joint damage in RA [ 10, 11].

In osteoporosis, a clear relationship has been established between levels of bone markers such as Ntx and the occurrence of skeletal complications, whether or not a patient has received bone-specific therapy.

In this study, we found higher expression of bone markers, such as ALP and OCN, and the transcription factors Runx-2 and osterix after stimulation of AS fibroblasts with CCL19/CCL21.

Some studies show normal 1 2 or low 3 4 levels of bone formation markers, such as osteocalcin or bone alkaline phosphatase (BAP), while other studies show elevated levels of these biomarkers.

The osteoblast-specific bone forming markers osteocalcin and osteoprotegerin were decreased in TH mice, whereas osteoclast-driven bone resorption markers such as IL-6 and RANKL were significantly elevated in the bone marrow and blood of TH mice.

MM patients show lower levels of bone formation markers, such as alkaline phosphatase (ALP) and osteocalcin (OC), and increased bone resorption markers [ 25].

After subcutaneous injection of denosumab, bone turnover decreases within 24 h as reflected by decreases in urinary and serum bone turnover markers, such as the urinary N-telopeptide/creatinin ratio and the serum N-telopeptide concentration.

Also, other bone turnover markers such as osteocalcin, procollagen type I N-terminal peptide (PINP), pyridinoline, N-telopeptide, and bone specific alkaline phosphatase (BALP) were not taken into consideration.