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Bone is comprised of an enormously hierarchical construction that promotes transportation of necessary fluids and solids, guaranteeing accurate function and growth.
Bone is comprised of 95% collagen type I, with fibronectin and laminin present within the bone marrow ECM (Vituri et al, 2000) and laminin also a key component of the sinusoidal basement membrane (Gu et al, 2003), so the upregulation of integrins that bind to these ECM components may explain the fact that breast cancer cells predominately metastasise to bone (Powell et al, 1991).
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The inorganic phase of bone is comprised primarily of very small mineralites.
The book is comprised of three sections.
The relationship between the cutting conditions and the cutting characteristics of cortical bone and cancellous tissue, of which bone is comprised, were evaluated.
Histological analysis reveals thickening of the cortical bone that is comprised of mature lamellar and woven bone with adjacent fibrocartilage surrounding coronoid islands [ 43, 44].
Bone strength is comprised of many components including, but not limited to bone architecture, geometry, cortical porosity and tissue mineralization density.
The bone matrix is comprised of various matrix proteins like collagen, fibronectin (FN), osteopontin, and FN is a known receptor for integrin α5β1 that helps in cell attachment.
The hematopoietic stem cells (HSCs) niche of the bone marrow is comprised of HSCs, osteoblasts, endothelial cells and a stromal component of non-hematopoietic multipotent cells of mesenchymal origin named "mesenchymal stem cells" (MSCs).
Standing at 6m tall (nearly 20') The Tower of Babel is comprised of 3,000 bone china shops all made by the artist.
At birth, the human craniofacial skeleton is comprised of 44 bones that develop via both endochondral and intramembranous ossification, depending on the bone.
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